May 30

Fructose and Metabolic Syndrome

Fructose is a key factor in the development of metabolic syndrome [See]

Fructose Impairs, Fish Oil Helps Brain Function
There is one more reason now to avoid fructose, or fruit sugar. A University of California Los Angeles (UCLA) study on rats by Rahul Agrawal and Fernando Gomez-Pinilla has shown that a diet high in fructose slows the brain, hampering memory and learning — and that omega-3 fatty acids can counteract the disruption. The study found that high sugar consumption impaired cognitive abilities and disrupted insulin signalling by engaging molecules associated with energy metabolism and synaptic plasticity; in turn, the presence of docosahexaenoic acid, an n-3 fatty acid, restored metabolic homeostasis.

  • Rahul Agrawal, Fernando Gomez-Pinilla. ‘Metabolic syndrome’ in the brain: deficiency in omega-3 fatty acid exacerbates dysfunctions in insulin receptor signalling and cognition. The Journal of Physiology. May 1, 2012;590:2485-2499. doi: 10.1113/jphysiol.2012.230078. [Full Text]
  • UCLA Press Release

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